Pathogens, Free Full-Text

Mycobacterium tuberculosis (Mtb) is a deadly pathogen and causative agent of human tuberculosis, causing ~1.5 million deaths every year. The increasing drug resistance of this pathogen necessitates novel and improved treatment strategies. A crucial aspect of the host–pathogen interaction is bacterial nutrition. In this study, Artemisia annua and Artemisia afra dichloromethane extracts were tested for bactericidal activity against Mtb strain mc26230 under hypoxia and various infection-associated carbon sources (glycerol, glucose, and cholesterol). Both extracts showed significant bactericidal activity against Mtb, regardless of carbon source. Based on killing curves, A. afra showed the most consistent bactericidal activity against Mtb for all tested carbon sources, whereas A. annua showed the highest bactericidal activity in 7H9 minimal media with glycerol. Both extracts retained their bactericidal activity against Mtb under hypoxic conditions. Further investigations are required to determine the mechanism of action of these extracts and identify their active constituent compounds.

Pathogens, Free Full-Text

Pathogens, Free Full-Text

Pathogens, Free Full-Text

Know your pathogens! Genaxxon bioscience - online shop

PDF) A framework for the study of zoonotic disease emergence and its drivers: Spillover of bat pathogens as a case study

PDF) Label-Free 3D Ag Nanoflower-Based Electrochemical Immunosensor for the Detection of Escherichia coli O157:H7 Pathogens

Pathogens, Free Full-Text

Development of specific pathogen-free (SPF) shrimp stocks and their application to sustainable shrimp farming - ScienceDirect

Pathogens, Free Full-Text, staphylococcus aureus

Pathogens, Free Full-Text, duda games gta rp

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis - The Lancet

Mouse hygiene status–A tale of two environments for mast cells and allergy - ScienceDirect